Director/PDMR shareholding

December 23, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that it was notified today that Werner Spinner, a Non-Executive Director of the Company, yesterday purchased 25,000 ordinary shares in the Company at 32 pence per ordinary share.

Werner Spinner is now beneficially interested in 134,868 ordinary shares in the Company representing 0.29 per cent. of the issued share capital.

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Director/PDMR shareholding

December 11, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) was notified today that Johan Goossens, a Non-Executive Director of the Company, today purchased 500,000 ordinary shares in the Company at a price of 12 pence per ordinary share.

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Director/PDMR shareholding

December 10, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) was notified yesterday that Johan Goossens, a Non-Executive Director of the Company, between 5 December and 9 December 2008 purchased 800,000 ordinary shares in the Company at a price of 14.5 pence per ordinary share.

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Director/PDMR shareholding

December 9, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that it was notified today that Werner Spinner, a Non-Executive Director of the Company, yesterday purchased 100,000 ordinary shares in the Company at a price of14 pence per ordinary share.

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Director/PDMR shareholding

October 23, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that it was notified today that Johan Goossens, a Non-Executive Director of the Company, yesterday purchased 100,000 ordinary shares in the Company at 38.30 pence per ordinary share.

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Director/PDMR shareholding

October 22, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that it was notified today that Marc Waeterschoot, the Executive Chairman of the Company, yesterday purchased 2,977,500 ordinary shares in the Company at 37.5 pence per ordinary share.

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Director/PDMR shareholding

September 26, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that it was notified today that Marc Waeterschoot, the Executive Chairman of the Company, yesterday purchased 421,000 ordinary shares in the Company at 65 pence per ordinary share.

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Director/PDMR shareholding

September 25, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that on Wednesday 24 September 2008, Rob Koremans, the CEO of the Company, purchased 35,000 ordinary shares in the Company at 65 pence per ordinary share; and, Arnoud van Tulder, the Chief Financial Officer of the Company, purchased 20,000 ordinary shares in the Company at 65 pence per ordinary share.

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Director/PDMR shareholding

September 24, 2008 Group News

Director’s Dealings

Cryo-Save Group N.V. (the “Company”) announces that it was notified today that Johan Goossens, a Non-Executive Director of the Company, yesterday purchased 100,000 ordinary shares in the Company at 71 pence per ordinary share; and, today purchased a further 150,000 ordinary shares in the Company at 70 pence per ordinary share.

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Director/PDMR shareholding/grant of options

May 22, 2008 Group News

Cryo-Save Group N.V. (“Cryo-Save” or “the Company”), Europe’s largest adult stem cell storage bank, announces that on 20 May 2008 the Company granted options to subscribe for ordinary shares in the Company under the Cryo-Save Group 2007 Share Option Scheme. The Company granted 175,000 options to Directors of the Company (as detailed below) and 175,000 options to certain other employees of the Company all at an exercise price of 210.2p per share, being the price equal to the arithmetic average of the closing mid-market price over the five dealing days prior to the date of the grant. All of these options are exercisable at any time from 21 May 2011 until 21 May 2018.

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